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dingbat
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« Reply #765 on: October 04, 2008, 06:29:24 PM » |
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Hey, db, isn't there something about a point at which melamine and cyanuric acid and/or uric acid saturates at some high level of exposure, forms precipitate in the kidneys, causing stones and nephron tubule damage which is permanent and can no longer be excreted?
3cat That is correct, not sure what the exposure level is though. Melamine by itself does not cause the kidney damage, only when it is mixed with other chemicals, CA, UREA, etc does it start to form the blockage and stones. The body will excrete, in half life, melamine in 3 hours, which means that it probably takes 24 hours before the levels have been reduced substantially. However that does not take into effect the addition of the other chemicals, who knows what those are, and what those half lives are. Don't know if studies have been done on mixing melamine/ca/urea/etc and at what proportions and what those half lives would be. So basically no one really knows how this crap will effect us, pets, babies, etc in the short and long terms. The studies would only be valid for whatever concentrations that were tested on, typically rodents, and then that may or may not be whatever concentrations we are seeing in the melamilk, or melavegetables, melawhatever. db
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I used to think that anyone doing anything weird was weird. I suddenly realized that anyone doing anything weird wasn't weird at all and it was the people saying they were weird that were weird.
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3catkidneyfailure
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« Reply #766 on: October 04, 2008, 06:33:35 PM » |
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Guess that's the problem. No one knows those levels. No one is going to voluntarily subject themselves or their children to scientific studies to find out. And countries everywhere continue to import this tainted cwrap. (I just became 21 -- sorry, I have a big mouth I guess or am really angry)
Anyway, if anyone wants to help organize some of the chaotic info in this thread since September 11, please PM me, and thank you.
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« Last Edit: October 04, 2008, 06:43:02 PM by 3catkidneyfailure »
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yl
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« Reply #767 on: October 04, 2008, 06:39:21 PM » |
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DB Thanks for the info. If melamine passes through the body in a short period of time is it excreted as melamine? If it mixes with other chemicals how much of the mix can the systems of animals and take before there is organ damage?
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dingbat
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« Reply #768 on: October 04, 2008, 06:56:30 PM » |
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DB Thanks for the info. If melamine passes through the body in a short period of time is it excreted as melamine? If it mixes with other chemicals how much of the mix can the systems of animals and take before there is organ damage?
YL Well sort of. If melamine is excreted through the urine, then it becomes mixed with uric acid, which then may make it more dangerous than it was to begin with. This may be a key element here. If a cow (for sake of example) eats some tainted grass and then urinated it out, onto the ground and then next year eats in the same area, it is now more toxic than the first year because it is mixed with uric acid and now will start to stay in the tissues longer. Then the third year would be worse, of course the original melamine is now at half life but the new compound, melamine/uric acid, it not studied for half life. I can see a vicious circle here, cumulative effects occurring by ingesting the melamine and then passing it through the body, then creating something more toxic, etc, etc. the FDA had said it over and over, and then will backtrack, but they continue to say, melamine does not belong in food, period. Maybe this is one of the unreported side effects, unknown side effects of melamine ingestion. db
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I used to think that anyone doing anything weird was weird. I suddenly realized that anyone doing anything weird wasn't weird at all and it was the people saying they were weird that were weird.
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yl
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« Reply #769 on: October 04, 2008, 07:34:55 PM » |
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In searching for melamine test on animals I found this patent. The dates are interesting or rather scary. This patent is for making feed with melamine in it. http://www.freepatentsonline.com/3653909.html
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lesliek
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« Reply #770 on: October 04, 2008, 07:55:22 PM » |
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We've been eating this s--t since the 70's ! What the h--l is wrong with our goverment !No wonder so many pets & pweople have kidney & liver problrms & diabetes.
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"the world's most inept extortionist"
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DMS
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« Reply #771 on: October 04, 2008, 08:25:04 PM » |
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Anyone searching the cryomazine to melamine angle, please be sure to search cyromazine as well. I'm not sure if these are two spellings of the same exact compound, but cyromazine does metabolize into melamine and is used on crops and in livestock. Does anyone know if these two things are the same? http://www.cdpr.ca.gov/docs/risk/rcd/cyromazine.pdfThe weight of scientific evidence did not support conducting an oncogenic risk assessment for melamine, a primary metabolite of cyromazine found in the rat. ___________________ There is a lot more info on cyromazine than cryomazine. My concern is whether or not there is a parent chemical (which is not being measured) that has degraded into melamine or if melamine alone was added and proceeded to degrade.
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None are more hopelessly enslaved than those who falsely believe they are free. -Johann Wolfgang von Goethe
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DMS
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« Reply #772 on: October 04, 2008, 08:46:57 PM » |
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This site has a lot of information on cyromazine and its residues on crops and in animals and different types of soil. Countries using cyromazine are also listed with approved crops and residue levels. The melamine aspect was not as well documented. Maybe it should be now, this is well worth looking over, residues and toxicity tests are listed. And as mentioned by db and others, I'm not sure what happens beyond the testing period as melamine and cyromazine accumulate in the soil: http://www.fao.org/ag/AGP/AGPP/Pesticid/JMPR/Download/2007_eva/Cyromazine.pdfDefinition of the residue In 1990, the JMPR defined the residue for cyromazine in food as cyromazine. At the 1992 JMPR, the possibility of including melamine in the definition was discussed, but the Meeting decided to maintain the previous definition as melamine was considered to be less toxic than cyromazine, and that melamine may have originated from sources other than from the use of cyromazine. Nevertheless the Meeting recognized that the monitoring of good agricultural practice in growing mushrooms under certain conditions was not possible when melamine was omitted from the residue definition. Data submitted to the present Meeting have shown that melamine is the main metabolite found in all crops and most animal products. Cyromazine is the major compound found in all crops, with the exception of mushroom, where melamine can be present at levels higher than cyromazine.-------------------------------------------------------------------------------- I believe the listed residual levels would also be dependent on the ratio in the spray as the tested rate is listed. If cyromazine is sprayed at a higher ratio or more often, I bet the residues would increase. The accumulation in the soil would most likely affect plant uptake as well. I will reread the info, but am not sure if that issue was addressed and explored.
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« Last Edit: October 04, 2008, 09:53:19 PM by DMS »
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None are more hopelessly enslaved than those who falsely believe they are free. -Johann Wolfgang von Goethe
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JJ
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« Reply #773 on: October 04, 2008, 08:49:59 PM » |
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In the link from yl it also makes mention that the cost of the melamine was too expensive? - well what did they use then instead - the waste water from the manufacture of melamine and add that to the feed for the livestock and swine, goats etc in order to have a place to get rid of it?
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'Life isn't about how to survive the storm, But how to dance in the rain.'
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lesliek
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« Reply #774 on: October 04, 2008, 08:55:33 PM » |
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Probably & then turn around & use the waste from them including urine. Yum !
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"the world's most inept extortionist"
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Poco
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« Reply #775 on: October 04, 2008, 10:14:31 PM » |
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http://scienceblogs.com/effectmeasure/2007/05/melamine_tastes_like_chicken.phpPosted by a 'GP', (General Practitioner?), during 2007 pet food recall: "Randolph, I think you misunderstand my intent.
I'm not saying that we should look at kidneys of those dying of non-renal causes in order to fix blame or cause a liability issue. What we should do, is look at them to determine if melamine polymer is collecting in detectable amounts in the population when sampled at random.
I wouldn't use people with renal disease as the cause of death because you cannot be sure whether the renal disease was caused by the melamine (if you find it) or if the melamine accumulation is due to pre-existing disease.
If you look for melamine in people who had no clinical kidney issues, then it's a case of 'no harm no foul'--you are not generating a situation of liability for anyone. But what you *are*doing, is determining if the melamine contamination in the food chain has been reaching humans, and if it has the *potential* to cause clinical problems.
If you find small amounts of it in the otherwise normal kidneys of human beings then that would prove that the food supply is contaminated sufficiently that humans are at risk *over a longer span of time* of developing the same renal problems as the pets did, which is basically to have their kidneys fill up with deposits of plastic. It would show that the problem has indeed entered the human food chain with potential significance, and that would allow clinicians to start looking for evidence of melamine as the cause in any otherwise explained kidney problems that might crop up in their patients.
Finding melamine in otherwise healthy folk will not, however, prove that the melamine causes harm. That would require additional study.
The medical community has to do something about this. We're the only ones who do not have a reason to bury the data; everyone else makes more money if they let people become sick or die. I'm just not plugged into 'the system' enough to initiate the effort.
Posted by: *** the GP | May 3, 2007 11:20 PM
And I'm thinking of a fairly small sample size--say 1000 corpses nationwide, chosen at modified-random to reflect the general population. The question to be answered is: has the melamine contamination of the food chain for humans reached a level where melamine can be detected in human kidneys?
You'd not be measuring morbidity or mortality, merely if the melamine exposure of your average Joe is enough to turn up in the kidneys.
Posted by: Lisa the GP | May 3, 2007 11:24 PM "
Posted by a 'DVM': "In physics, each action has an equal and opposite reaction. In animal physiology, each action has thousands of reactions..
...the point being that nothing in the body happens in isolation. Yes, this chemical by itself will accumulate in the body at any level but the more important concern is how does this chemical interact with the other foreign particles circulating daily mainly due to additives or intentional or unintentional adulterants of processed foods.
You will often hear as with the chickens and pigs that a Health Risk Analysis has indicated there is no danger from the levels in these foods...
...but the fact is that they treat the situation in isolation...there is no danger if this is the only source of the contaminant and there are no other contaminants that will chemically interact.
Dioxin is always safe if you are isolating it in one food source and ignoring the rest.
Health Risk Analysis are the processed food lobbyists best friend.
Revere. What if there is a small part of melamine in one food you eat for supper and extraneous formaldehyde (embalming fluid) in the food right beside the melamine contaminated food?
Posted by: *** DVM | May 9, 2007 9:48 AM "
And: "Lisa/Revere..... This stuff accumulates in the kidneys of animals right and not the general tissues?
BTW a little bird in government told me that this stuff may have been coming into the country for four years from one to three sources. The Chinese are scrambling to shut them down. Under their laws if the acts caused human death and its attributable then they will be shot or hanged.
Incredibly stupid thing to do and as with the glycol deaths in Panama they will pay for it with their lives.
Posted by: ****** | May 9, 2007 1:08 AM "
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Don't experiment on me!
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3catkidneyfailure
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« Reply #776 on: October 05, 2008, 08:47:16 AM » |
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http://www.chicagotribune.com:80/news/chi-ap-wi-mathison-qampa,0,2060475.storyDairy security specialist aims to prevent disaster By M.L. JOHNSON | Associated Press Writer 12:00 AM CDT, October 5, 2008 MADISON, Wis. - The spread of disease -- accidentally or intentionally -- through the nation's livestock could cripple dairy and meat producers and create a severe food shortage. To prevent such a catastrophe, federal and state officials have been working with farmers to improve safeguards and emergency plans. Matt Mathison is helping lead the effort as chairman of the Wisconsin Agro-Security Resource Network and a member of the FBI Agro-Security Team of Wisconsin ...
Mathison: The U.S. food supply is highly regulated and very inspection-oriented. We know that has created a very safe food supply historically, and continues. The food grown outside the country has varying levels of regulatory and inspection oversight. There is some inspection at the border as it comes in, but that food supply may not be held to the same inspection and regulatory standard as the U.S. productsTwice in two years, 2007 with companion animals and 2008 with China's children, through the little understood mechanism of melamine degradation, the US food supply has been subject to lethal threat on a massive scale. Apparently there is so much of this adulterant in the global food supply, it only takes minimal addition by unknown suppliers in the global food chain to tip the scale causing illness and death among animals and human beings. The time to argue about how melamine causes the phenomenon is a subject for future study. The time to stop the spread of melamine adulteration was March of 2007. And China in September of 2008 proves it hasn't been done. The US government is failng the US consumer by not acting right now. This is a load of unspeakable d*ng: http://ap.google.com/article/ALeqM5i1PW8Su6EECm-m22gV1dABkLdHJQD93KA1V80China says new tests show milk free from melamine 4 hours ago (October 5, 2008) BEIJING (AP) — China's food safety watchdog said Sunday no traces of the industrial chemical melamine were found in new tests of milk powder sold domestically, as officials sought to restore public trust in milk supplies.Every other food safety authority in the entire world agrees there would be trace levels of melamine from production processes and packaging alone. This food source, China, does not know how to tell the truth.
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« Last Edit: October 05, 2008, 09:14:17 AM by 3catkidneyfailure »
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3catkidneyfailure
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« Reply #777 on: October 05, 2008, 09:19:52 AM » |
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http://miadhu.com.mv/news.php?id=7999Sunday, October 5, 2008: Maldivian authorities have ordered to destroy more than 20,000 bottles of Dutch Lady Milk manufactured in China in the wake of detection of melamine in Chinese milk products which has set off a global food safety scare. The authorities have also suspended sale and import of all Chinese manufactured dairy products. http://newsinfo.inquirer.net/breakingnews/world/view/20081005-164710/Milk-scandal-sours-Chinas-White-RabbitMilk scandal sours China's White Rabbit Agence France-Presse First Posted 11:24:00 10/05/2008 SHANGHAI -- China's creamy White Rabbit sweets survived Japan's World War II occupation and the Communist Revolution, but the tainted milk crisis has cast doubt on the future of the well-known brand. But White Rabbit's manufacturer, Guan Sheng Yuan, has kept mum about the scandal, even as the list of multinationals recalling products grows. The silence stands in sharp contrast to last year when -- amid allegations that its famous confectionery contained formaldehyde -- the company's general manager called a press conference to pop sweets into his mouth to show they were safe. But unlike other companies, White Rabbit's problems do not stem from rogue suppliers. Guang Shen Yuan gets its milk from its parent company, one of the tarnished milk producers, Shanghai Guangming (Bright) Dairy and Food Co..
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« Last Edit: October 05, 2008, 09:42:14 AM by 3catkidneyfailure »
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3catkidneyfailure
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« Reply #778 on: October 05, 2008, 09:44:08 AM » |
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http://lawprofessors.typepad.com:80/healthlawprof_blog/2008/10/fda-sets-safety.htmlFDA Sets Safety Threshold for Contaminant Melamine October 4, 2008 The FDA guidelines were issued to help federal and state investigators checking for contaminated Chinese products as they enter the country and in Asian grocery stores. Sundlof said the agency's goal is to identify products with potentially dangerous levels of melamine, rather than to find each small instance of contamination. But Rep. Rosa DeLauro (D-Conn.), head of a House subcommittee that oversees FDA funding, criticized the agency for saying there could be safe levels of melamine in foods. "While other countries throughout the world, including the European Union, are acting to ban melamine-contaminated products from China, the FDA has chosen to establish an acceptable level for melamine in food in an attempt to convince consumers that it is not harmful," DeLauro said in a statement. "Not only is this is an insult to consumers, but it would appear that the FDA is condoning the intentional contamination of foods."
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straybaby
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« Reply #779 on: October 05, 2008, 10:18:13 AM » |
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3Cat, from your link: Sundlof said the agency's goal is to identify products with potentially dangerous levels of melamine, rather than to find each small instance of contamination. WTF?! Have they learned NOTHING from the PFR?!
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