Thank you, yl, for reposting this interesting results. Something for all of us to keep in mind. The symptoms of the poisoning in humans are very much like what one of my dogs suffered.
Here is an unfortunate, but comprehensive article on chaconine and solanine experiments with animals and humans. I am a vegetarian; and I do apologize if the animal experiments listed offend anyone. I find them disturbing, but thought they may be a useful comparison. Also, the data on some accidental poisonings:
http://www.inchem.org/documents/jecfa/jecmono/v30je19.htm"Assuming an intake of 200 g potatoes and a
bw of 40 kg (age = 11-14 years), the reviewers estimate that the
intake of 'solanine' by the schoolboys would therefore have been
approximately 1.4-1.6 mg/kg bw. Because of the small margin of
safety between normal potatoes and toxic potatoes, the authors
speculated that in toxic potatoes other toxic steroids besides
glycoalkaloids may be synthesized, such as sapogenins and saponins,
which might enhance the toxicity of solanine alkaloids by promoting
gastro-intestinal absorption or other means (McMillan & Thompson,
1979)."
Here are some of the symptoms; I highlighted the ones I observed in my dog earlier this year. I do not know what caused his illness, other than suspecting the food. This news from yl really makes me wonder, though. He also had liver damage and a temporary shut down of digestion, dehydration, drooling and staring, odd behavior, persistant hair loss and skin infections (hair loss is listed elsewhere on this link above):
"
acute gastrointestinal upset with diarrhoea, vomiting and severe
abdominal pain. In more severe cases,
neurological symptoms,
including drowsiness and apathy, confusion, weakness, and vision
disturbances, followed by unconsciousness and, in some cases, death
have also been reported. The vital signs include fever, rapid and
weak pulse, low blood pressure and
rapid respiration. {panting, in his case} "
Just came across this. I've posted at length in the Weruva thread regarding Sylvester's STINKY diarrhea issues with Weruva. It is a wet food. They have acknowledged to me using potato starch as a thickener. I haven't seen any of the other symptoms above.
Should I be concerned? This appears to be the only food on the market he can eat. His vet is aware of the diarrhea issues, but hasn't connected it to Potato, though I don't think I've spoken with her since I got that information.
I'm not aware of anyone else reporting diarrhea with Weruva, so hopefully this is a false alarm......