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Author Topic: melamine and cyanuric acid in dogs and cats in 2004 and 2007.  (Read 22503 times)
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mal
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« on: September 28, 2007, 08:36:32 PM »



Outbreaks of renal failure associated with melamine and cyanuric acid in dogs and cats in 2004 and 2007.

Athens Veterinary Diagnostic Laboratory, College of Veterinary Medicine, University of Georgia, Athens, GA, 30602. cabrown@vet.uga.edu.

Sixteen animals affected in 2 outbreaks of pet food-associated renal failure (2 dogs in 2004; 10 cats and 4 dogs in 2007) were evaluated for histopathologic, toxicologic, and clinicopathologic changes. All 16 animals had clinical and laboratory evidence of uremia, including anorexia, vomiting, lethargy, polyuria, azotemia, and hyperphosphatemia. Where measured, serum hepatic enzyme concentrations were normal in animals from both outbreaks. All animals died or were euthanized because of severe uremia. Distal tubular lesions were present in all 16 animals, and unique polarizable crystals with striations were present in distal tubules or collecting ducts in all animals. The proximal tubules were largely unaffected. Crystals and histologic appearance were identical in both outbreaks. A chronic pattern of histologic change, characterized by interstitial fibrosis and inflammation, was observed in some affected animals. Melamine and cyanuric acid were present in renal tissue from both outbreaks. These results indicate that the pet food-associated renal failure outbreaks in 2004 and 2007 share identical clinical, histologic, and toxicologic findings, providing compelling evidence that they share the same causation.
PMID: 17823396 [PubMed - in process]


http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=17823396&ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

So this is not the first time that melamine and cyanuric acid has been found to be killing our pets!! What is going on. Can anyone find more information on the 2004 incident?



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straybaby
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« Reply #1 on: September 28, 2007, 10:06:22 PM »

an outbreak would be more than 2, right? and it sounds like the other 14 are the menu foods test animals, so is that an outbreak?

"All animals died or were euthanized because of severe uremia."

so why doesn't this fit for me?
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straybaby
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« Reply #2 on: September 28, 2007, 10:38:40 PM »

we were 100% raw in 2004. but i was very active at the shelters and one has a pet supply store attached to the shelter. and if for some reason i was zoned out, several of my friends also were spending time there and had a long term relationship with them. if they knew, i'm sure i would have heard!

silent recalls anyone . . . . ?
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purringfur
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« Reply #3 on: September 29, 2007, 04:38:23 AM »

PEDIGREE SUED BY PET OWNERS, 2004

Arsenic & mercury also found

http://ukrmb.co.uk/images/Pedigree%20sued%20by%20dog%20owners.pdf

http://www.pets.ca/forum/archive/index.php/t-7215.html

http://lists.envirolink.org/pipermail/ar-news/Week-of-Mon-20040705/026721.html

http://translate.google.com/translate?hl=en&sl=zh-TW&u=http://long-life-vet.myweb.hinet.net/petfood.html&sa=X&oi=translate&resnum=5&ct=result&prev=/search%3Fq%3Deffem%2Bfoods%2Btaiwan%2Bkidney%2Bfailure%2B2004%26start%3D10%26hl%3Den%26rls%3DGGLG,GGLG:2005-39,GGLG:en%26sa%3DN

« Last Edit: September 29, 2007, 05:17:49 AM by purringfur » Logged

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mal
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« Reply #4 on: September 29, 2007, 06:41:35 AM »



Klondike:

Kidney failure may be the reason the animals are dying, but the initiating
factor of the renal disease has not been determined..."

Thank you for your find on this information.


It was interesting in the article that I came across that they said:

These results indicate that the pet food-associated renal failure outbreaks in 2004 and 2007 share identical clinical, histologic, and toxicologic findings, providing compelling evidence that they share the same causation

Does this mean that this systematic poisoning of our furkids has been going on for over 3 years? Why do the outbreaks only occur sporadically? What else is going into pet food?

Too many questions..no good answers.

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straybaby
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« Reply #5 on: September 29, 2007, 04:57:39 PM »

"How could this have happened twice?"

simple. they handled the first one like this one. acted like nothing much happened and denied. kept the losses to a minimum on paper and shifted the blame. the only thing the pet owners know from 2004 and 2007 is pet food killed or sickened their pets.
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JustMe
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« Reply #6 on: September 29, 2007, 05:39:34 PM »

I found this:

Here is a scientific report on 3 dead dogs in Korea in 2004 that had renal failure from unknown cause and were all eating same dog food for about a month.
http://vetsci.org/2006/pdf/299.pdf


My impression of this report is they hypothesize the dogs died of mycotoxicosis, but they aren't sure.

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DMS
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« Reply #7 on: September 29, 2007, 09:23:22 PM »

I read it and came to the same conclusion, but wonder why in this day and age--when they can genetically alter organisms, map genetic sequences of entire life forms--they can not be sure how these pets died.  It defies reasonable logic. I'm hoping we find a more recent article that is more conclusive.  How can this be that no one knows?  It's just like the open ended melamine risk assessment we have been given here.  Melamine is implicated, but proven safe.  Now what do we make of that?  A hill of beans!  Anyway, back to the Asia 2004, they have to know. I don't understand how something so big can be covered up.  From one article I read, some 5000+ pet owners were compensated in Asia, with many declining, all they wanted was the truth to be known.  And it never even got out.  (I think I do vaguely remember a blurb!  blurbette, maybe) Something is so wrong, it reeks to me of spillover into human food--i think that is why the secret is being guarded so carefully.  But sooner or later someone will talk.  I just hope they don't wait 20 years, or even 2!  Sorry for the paranoid diatribe, but I am getting really frustrated with this again. 
OOOhhhmm....
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straybaby
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« Reply #8 on: September 29, 2007, 10:29:31 PM »

"It's just like the open ended melamine risk assessment we have been given here."

that wasn't a risk assessment, it was a risk assumption.  Angry
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JJ
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« Reply #9 on: September 30, 2007, 06:46:44 PM »

DMS looks like it was kept on the hush hush so what is happening here would not have happened in 2004. Namely people home cooking and turning away from all the suspect kibble that is still making pets sick and in some cases killing them. IMO feel that this is a plan put together by all the vets who needed money in their clinics, the ingredient manufacturers and the pet food companies. They all kick-back the profits to each other while watching and letting  out pets get sicker and sicker and then dropping dead. And not a one of em gives a rats ass about any of the pets. Does it always come back to the money - to the greedy almighty money they can make no matter who suffers?
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catbird
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« Reply #10 on: October 19, 2007, 01:20:41 PM »

I have been pondering and looking into this topic ever since it was first posted, since I had a strange and sudden cat death in 2004, which I have posted about on another thread awhile back.  As I dug deeper into the links on this thread, imagine my surprise!  These recalls in Asia occurred in September 2004. 

My beloved sixteen-year-old Mac died on September 23, 2004.  He was running and playing on a Sunday, sick on a Wednesday, and was euthanized on the Thursday evening.   The vet clinic had tried all day to save him. We never figured out exactly what had happened.  He wa an indoor cat who did not have access to poisons.

Why is this significant?  Because this cat was eating Whiskas pouch food, a Mars/Pedigree product.  I had five cats at the time and he was the only one who ate this food.  Mars/Pedigree appears to have been the food implicated in the Asian recalls.

It has been happening for a long, long time.  It has been covered up.  I am convinced now that poisoned pet food killed my sweet orange boy.
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menusux
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« Reply #11 on: October 19, 2007, 02:13:18 PM »

What I've found re: the Effem/Mars/Pedigree recall in 2004, indicates that it was some sort of mold and that it was centered in their factory in Thailand:

http://goliath.ecnext.com/coms2/gi_0199-153148/Pedigree-brand-dog-food-recalled.html#abstract

Asian Economic News 15 March 2004

"BANGKOK, March 12 Kyodo

The makers of Pedigree brand dog food and Whiskas brand cat food have recalled products manufactured in Thailand and sold in Japan, South Korea and Southeast Asia after reports of increased renal illness among dogs in Taiwan, according to a company statement Friday.

"Effem Foods (Thailand) Co., a unit of food and confectionary giant Mars. Inc., said in a statement that it has recalled the dry dog and cat food ''because of concerns over raw material quality at a manufacturing plant in Thailand.''

"It said it had found mold in raw materials Wednesday..."

And this is all one gets of the article unless one subscribes.

http://www.news24.com/News24/world/news/0,,2-10-1462_1495111,00.html

News24.com

Pedigree recalls dog food
08/03/2004 15:15  - (SA)   

"Taipei - US dog food maker Pedigree began recalling its dry dog food from Taiwan shelves on Monday following the deaths of hundreds of Taiwan puppies from kidney failure.

""Consumers can return dry Pedigree dog food to pet stores where they bought it and get a refund. A new batch of Pedigree dog food will be ready in a month's time," said Chen Hsing-wen, spokesperson for Eiffem Foods, Taiwan's distributor of Pedigree.

""This does not mean there is something wrong with Pedigree. We are doing this out of the sense of responsibility and to show we are concerned about the dogs (dying)," she said.

"Rumours began circulating on the internet early this year that hundreds of pet dogs in Taiwan had fallen ill after eating Pedigree - 30 of them dying from massive kidney failures.

"Further reports claimed that most of the dogs that were dying were puppies, which has confused many of Taiwan's health officials and vets as it is usually only adult dogs that die from kidney failures.

"Some dog owners suspect that this specific batch of Pedigree, which was made in Thailand, might have been contaminated by the recent outbreak of the bird flu epidemic in that country.

"However, tests done by the Taiwan branch of the Switzerland-based SGS Laboratory and by Taiwan's Department of Agriculture recently showed that Pedigree is safe for canine consumption.

"Eiffem Foods Taiwan has put up one million Taiwan dollars to help authorities and health officials find out the cause of the dogs' mysterious deaths. - Sapa-dpa"

Just as the melamine couldn't be found in the Pingyang Pet/Shanghai Bestro chicken jerky treats by anyone other than a lab WalMart hired, and the acetaminophen is only found by ExperTox.  SGS, above, is claimed to be used by Waggin Train--they can't find out what's wrong with those either.

http://www.marketwatch.com/news/story/your-dog-treats-safe-they/story.aspx?guid=%7B547145B8-DF96-4A8D-B6A8-A8E364D9B8DC%7D

August 23, 2007

"Waggin' Train Brand has not been pulled from store shelves and is not and never has been part of a recall," stated Jerry Peters, President of ADI Pet, Inc.

"ADI Pet products as well as facilities are regularly inspected by our retailers and SGS, one of the world's largest and most respected inspection companies."
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Trudy
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« Reply #12 on: October 19, 2007, 04:34:28 PM »

This is just crazy. I never heard of this. they sure kept it quite. Can you tell Me what kinds of cat food there was?
and We did have a dog, Lab, die of something a couple of years ago that the vet never did figure out.
But I lost one of My sweetest show cats last year of kidney problems.. We never did figure that one out either. she was so young. Hmmmmmmmmmmm.
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Carol
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« Reply #13 on: February 29, 2008, 01:06:45 PM »

I am posting this as a new topic as I think it is important---I found this link this am but mal found it back in September but I can't believe I didn't see it then---it is worth the read and the $10.00 access fee IMHO!  I can not believe this has stayed under the radar!!! Huh


I just want as many to see this as possible----so I'm cross posting it to three places (sorry JustMe)

http://jvdi.org/cgi/content/abstract/19/5/525

http://findarticles.com/p/articles/mi_m0WDP/is_2004_March_15/ai_114410165

I edited the title---as reading this article it is NOT a question that it was melamine and CA in the renal tissues from BOTH outbreaks--

I wonder if menusux can trace back the suppliers of Effem Foods (Thailand) Co.as she/he does so well?

And I want Mike Floyd to see this as well so AAFCO casn't hide behind the "this only happened once" theory!!

« Last Edit: March 03, 2008, 07:43:55 AM by Carol » Logged

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Carol
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« Reply #14 on: March 04, 2008, 12:35:55 PM »

There's more to this posted at Pet connection---they are running this now

http://www.petconnection.com/blog/2008/03/04/study-says-killer-combination-turned-up-in-pet-food-before-2007-recall/#comment-237703
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“Never doubt that a small group of thoughtful, committed citizens can change the world; indeed, it’s the only thing that ever has.” — Margaret Mead

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