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Author Topic: Breaking -Canada halts imports of USA Livestock feed - melamine + cyanuric acid  (Read 20305 times)
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petslave
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« Reply #45 on: July 16, 2007, 12:09:39 PM »

It looks like lysine is added to many pet foods, and many studies show the cheaper l-lysine sulphate to be as 'good' as the l-lysine HCL.

So maybe this last round is from contaminated lysine sulphate?
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petslave
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« Reply #46 on: July 16, 2007, 12:35:26 PM »

They are talking about monkeying with the genetic makeup of the bacteria used to create lysine in this paper:

http://www.springerlink.com/content/h88tqln4anere566/

"the availability of the Corynebacterium glutamicum genome sequence has a major impact on the improvement of the biotechnological manufacture of lysine. In this context, all genes of the carbon flow from sugar uptake to lysine secretion have been identified and are accessible to manipulation. The whole sequence information gives access to post genome technologies such as transcriptome analysis, investigation of the proteome and the active metabolic network."
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petslave
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« Reply #47 on: July 16, 2007, 01:00:11 PM »

OK, I have to take a break to rest my mind from google research.  I'm trying to find links somewhere in these items:
1.  lysine production by Corynebacterium glutamicum bacteria (which has an alternate name)
2.  Problems in the production that could create cyanuric acid cia the bacteria or process/machinary/chemicals used
3.  EU's problem with lysine sulphate not created by this method (was it contaminated?)
4.  genetically altered Corynebacterium glutamicum (can it convert atrazine to CA, etc.) 
5.  link of the bacteria or lysine to CA &/or acteaminophen (if you put any of these 2 together in a search lots comes  up but no direct links.)
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petslave
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« Reply #48 on: July 16, 2007, 01:40:11 PM »

I re-read the original link & the lysine is from China, no US link on that one.

Still, it's added to pet feed, so maybe that's where ours is coming from?
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yl
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« Reply #49 on: July 16, 2007, 02:07:32 PM »

 the companys named above ADM, Cargill have plants in China along with Dupont. Check http://www.transnationale.com
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petslave
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« Reply #50 on: July 16, 2007, 06:42:50 PM »

Yes, & I imagine like every other supplement it is now being mostly made in China instead of the US.
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Donna
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It's PEACE, not war & greed, earthlings!


« Reply #51 on: July 17, 2007, 05:27:00 AM »

OK, I have to take a break to rest my mind from google research.  I'm trying to find links somewhere in these items:
1.  lysine production by Corynebacterium glutamicum bacteria (which has an alternate name)

Petslave, here is the Patent 7 of 177 entitled, Nucleotide sequences for transcriptional regulation in corynebacterium glutamicum

[begin quote]
United States Patent  7,141,388
Crafton, et al.  November 28, 2006 

Nucleotide sequences for transcriptional regulation in corynebacterium glutamicum

Abstract

The invention relates to isolated polynucleotides from Corynebacterium glutamicum which are useful in the regulation of gene expression. In particular, the invention relates to isolated polynucleotides comprising C.glutamicum promoters which may be used to regulate, i.e., either increase or decrease, gene expression. In certain embodiments, isolated promoter sequences of the present invention regulate gene expression through the use of exogenous or endogenous induction. The invention further provides recombinant vectors and recombinant cells comprising isolated polynucleotides of the present invention, preferably in operable association with heterologous genes. Also provided are methods of regulating bacterial gene expression comprising growth of a recombinant cell of the present invention. In particular, the present invention provides methods to regulate genes involved in amino acid production comprising growth of a recombinant cell of the present invention. In certain embodiments, the present invention provides methods of regulating gene expression in bacteria, particularly Corynebacterium species, especially of the genus Corynebacterium, comprising fermentation growth of a recombinant cell of the present invention, where metabolite concentrations, temperature, or oxygen levels are manipulated to regulate gene expression.

Inventors:  Crafton; Corey M. (Decatur, IL), Rayapati; P. John (Monticello, IL) 
Assignee: Archer-Daniels-Midland Company (Decatur, IL)
 
Appl. No.:  09/987,763
Filed:  November 15, 2001

Description

... In one particularly preferred aspect of this embodiment, an isolated polynucleotide is provided, comprising a first nucleic acid as described above; and a second nucleic acid, which encodes a component of an amino acid biosynthesis pathway. Examples of amino acid biosynthesis pathways included in this aspect of the invention are the enzymatic pathways that result in the synthesis of L-glycine, L-alanine, L-leucine, L-methionine, L-phenylalanine, L-tryptophan, L-lysine, L-glutamine, L-glutamic acid, L-serine, L-proline, L-valine, L-isoleucine, L-cysteine, L-tyrosine, L-histidine, L-arginine, L-asparagine, L-aspartic acid, and L-threonine.

In a preferred aspect of this embodiment, the second nucleic acid encodes one of the following components of the L-lysine biosynthesis pathway: aspartokinase, aspartate beta-semialdehyde dehydrogenase, diaminopimelate dehydrogenase, diaminopimelate decarboxylase, dihydrodipicolinate synthetase, dihydrodipicolinate reductase, or pyruvate carboxylate.

In one particularly preferred aspect of this embodiment, an isolated polynucleotide is provided, comprising a first nucleic acid as described above; and a second nucleic acid, which encodes a component of an amino acid biosynthesis pathway. Examples of amino acid biosynthesis pathways included in this aspect of the invention are the enzymatic pathways that result in the synthesis of L-glycine, L-alanine, L-leucine, L-methionine, L-phenylalanine, L-tryptophan, L-lysine, L-glutamine, L-glutamic acid, L-serine, L-proline, L-valine, L-isoleucine, L-cysteine, L-tyrosine, L-histidine, L-arginine, L-asparagine, L-aspartic acid, and L-threonine.

In a preferred aspect of this embodiment, the second nucleic acid encodes one of the following components of the L-lysine biosynthesis pathway: aspartokinase, aspartate beta-semialdehyde dehydrogenase, diaminopimelate dehydrogenase, diaminopimelate decarboxylase, dihydrodipicolinate synthetase, dihydrodipicolinate reductase, or pyruvate carboxylate. ...
[end quote]

Here is Patent 1 of 1, entitled, Promoter DNA fragment from coryneform bacteria

[begin quote]
United States Patent  5,693,781
Zupancic, et al.  December 2, 1997 

Promoter DNA fragment from coryneform bacteria

Abstract

Coryneform bacteria promoter DNA fragments are disclosed having greater promoter strength in Coryneform bacteria cells than the tac promoter obtained by fusing Escherichia coli trp promoter and lac promoter. The promoter function of some of the promoter DNA fragments is controllable by replacing at least one of the culture-medium ingredients with at least one other ingredient. The sizes and nucleotide sequences of such promoter DNA fragments are also disclosed.

Inventors:  Zupancic; Thomas J. (Worthington, OH), Yukawa; Hideaki (Inashiki-gun, JP) 
Assignee: Mitsubishi Chemical Corporation (Tokyo, JP)
 
Appl. No.:  08/076,091
Filed:  June 15, 1993

Claims

What is claimed is:

1. An isolated DNA fragment which is obtained from coryneform bacteria chromosomal DNA and which is functional as a promoter in coryneform bacteria cells, wherein said DNA fragment has a greater promoter strength in coryneform bacteria cells than does a tac promoter in coryneform bacteria cells.

2. The isolated DNA fragment as claimed in claim 1, wherein said coryneform bacteria chromosomal DNA is chromosomal DNA obtained from Brevibacterium flavum MJ-233 (FERM BP-1497).

3. An isolated DNA fragment which is obtained from coryneform bacteria chromosomal DNA and which is functional as a promoter in coryneform bacteria cells and has greater promoter strength in coryneform bacteria cells than does a tac promoter in coryneform bacteria cells, wherein said promoter DNA fragment includes at least one of nucleotide sequences SEQ ID NOS. 1 to 12:

SUMMARY OF THE INVENTION

Accordingly, an object of the present invention is to obtain a promoter DNA fragment which shows the expression of a gene of interest in coryneform bacteria at a high rate. More particularly, an object of the present invention is to obtain from the chromosome of a coryneform bacterium a promoter DNA fragment having greater promoter strength than the above-described E. coli tac promoter, and to obtain from the chromosome of a coryneform bacterium a promoter DNA fragment which is useful for controlling the expression of a gene of interest in a coryneform bacterium.

The inventors of the present invention have found that such a promoter DNA fragment can be obtained from coryneform bacteria by using a novel promoter probe shuttle vector constructed by the inventors. The promoter probe shuttle vector comprises:

a) a replication origin DNA region that is functional in Escherichia coli,

b) a replication origin DNA region that is functional in coryneform bacteria,

c) a DNA region including a selectable marker gene,

d) a DNA region including a reporter gene, the DNA region including a gene which lacks its own promoter region and differs from the selectable marker gene of C) in phenotype, and

e) a transcription terminator located in the upstream from the DNA region d) including the reporter gene.

Based on the above finding, the invention provides:

(1) a promoter DNA fragment which is obtained from a chromosome of a coryneform bacterium and is functional in coryneform bacteria, the promoter DNA fragment having a greater promoter strength in coryneform bacteria than the tac promoter, and

(2) a controllable promoter DNA fragment which is obtained from a chromosome of a coryneform bacterium and is functional in coryneform bacteria, wherein the promoter function of the controllable promoter DNA fragment is controllable by replacing at least one substance which is contained in the culture medium for the host coryneform bacterium and is assimilable by the host coryneform bacterium, with at least one other substance which is assimilable by that the host coryneform bacterium.
[end quote]

If you desire additional information, which I can provide through Patents, please feel free to list what you need, or contact me.

Sincerely,
Donna


 ~The dead cannot cry out for justice; it is a duty of the living to do so for them~
    Lois McMaster Bujold, 2002 Diplomatic Immunity, US Science Fiction Author
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Disclaimer:  Opinions, thoughts & premises are my own, except links & quotes.

"Your task is not to seek for love, but merely to seek and find all the barriers within yourself that you have built against it."  Rumi
Donna
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Posts: 241

It's PEACE, not war & greed, earthlings!


« Reply #52 on: July 17, 2007, 05:49:47 AM »

Hi All!

I am still working on the 1 of 1 Patents.  I thought I would have the findings up by now, but each takes me to another Patent of even grandiose proportions and I now have 25 pages in the word processing avenue!   Maybe one day I will quit my curiosity factor and stick to the "task at hand", but plant vectors, Melamine Cyanurate (the salt of Melamine and Cyanuric Acid producing cyanuric acid in the urine of cats and dogs, which was my original thought as to contamination,) atrazine (head's up, the Patents lead to producing "salts" and speak of "melamine peroxide" and I am still looking at more, including WO Patents) and even Corynebacterium glutamicum bacteria (before I saw petslave's requested information) caught my eye and led to other feed and chemical searches.  So, I do apologize for not getting this information up on the board, but as I stated, it is still a work in progress.

However, this particular Patent, entitled, Embedding and encapsulation of controlled release particles stood out glaringly.  Basically, the notion of the invention encapsulates a variety of components so the finished dry product, or the desired end result, will slowly release its content when in the digestive tract without degradation.

The lists of "additional" components are astonishing right down to the inclusion of acetaminophen, and the foods they "can" appear in.  With respect to this novel invention, I am researching the "latest" Patents, and again apologize that I cannot offer more at this particular time.

[begin quote]
 ( 1 of 1 )

--------------------------------------------------------------------------------
United States Patent  6,190,591
van Lengerich  February 20, 2001  

--------------------------------------------------------------------------------
Embedding and encapsulation of controlled release particles


Abstract

Controlled release, discrete, solid particles which contain an encapsulated and/or embedded component such as a heat sensitive destruction or readily oxidizable pharnaceutically, biologically, or nutritionally active component are continuously produced without substantial destruction of the matrix or encapsulant. A release-rate controlling component is incorporated into the matrix to control the rate of release the encapsulant from the particles. the additional component may be a hydrophobic component or a high water binding capacity component for extending the release time. The plasticizable matrix material, such as starch, is admixed with at least one plasticizer, such as water, and at least one release-rate controlling component under low shear mixing conditions to plasticize the plasticizable material without substantially destroying the at least one plasticizable material and to obtain a substantially homogeneous plasticized mass. The plasticizer content is substantially reduced and the temperature of the plasticized mass is substantially reduced prior to admixing the plasticized mass with the encapsulant to avoid substantial destruction of the encapsulant and to obtain a formable, extrudable mixture. The mixture is extruded though a die without substantial or essentially no expansion and cut into discrete, relatively dense particles. Release properties may also be controlled by precoating the encapsulant and/or coating the extruded particles with a film-forming component.


--------------------------------------------------------------------------------
Inventors:  van Lengerich; Bernhard H. (Plymouth, MN)  
Assignee: General Mills, Inc. (Minneapolis, MN)
 
Appl. No.:  09/269,763
Filed:  May 17, 1999
PCT Filed:  October 27, 1997  
PCT No.:  PCT/US97/18984  
371 Date:  May 17, 1999  
102(e) Date:  May 17, 1999  
PCT Pub. No.:  WO98/18610  
PCT Pub. Date:  May 07,  

... DETAILED DESCRIPTION OF THE INVENTION

The additional components or ingredients used to control the rate of release of the encapsulant may be used in amounts up to about 70% by weight, preferably from about 5% by weight to about 50% by weight, most preferably from about 10% by weight to about 35% by weight, based upon the weight of the matrix material, such as starch.

Active components which may be encapsulated or embedded in the matrixes in accordance with the present invention include pharmaceutical compositions or compounds, nutraceutical compositions or compounds, nutritional components, or biologically active components, flavorants, fragrances, detergents or surface-active compositions. The pharmaceutical compounds or compositions may, for example, include antibiotics, analgesics, vaccines, antiinflammatory agents, antidepressants, anti-viral agents, anti-tumor agents, enzyme inhibitors, formations containing zidovudine, macromolecular polypeptides, aromatic nitro and nitroso compounds and their metabolites useful as anti-viral and anti-tumor agents, HIV protease inhibitors, viruses, and steroids, mixtures thereof, and the like. [emphasis mine]

Nutraceutical components may include components which promote health or prevent disease or enhance well-being such as antioxidants, phytochemicals, hormones, vitamins such as Vitamin C and Vitamin E, pro-vitamins, minerals, microorganisms such as bacteria, fungi, and yeast, prebiotics, probiotics, trace elements, essential and/or highly unsaturated fatty acids such as omega-3 fatty acids, and mid-chain triglycerides, nutritional supplements, enzymes, pigments, oligopeptides, dipeptides, and amino acids. [emphasis mine]

Biologically active components which may be encapsulated include agriculturally useful compositions to either prevent infestation such as herbicides, pesticides, insecticides, rodenticides, fingicides, mixtures thereof, and the like or to promote growth such as hormones, fertilizers, or other growth stimulating agents. [emphasis mine]

Exemplary of the active components which may be encapsulated or embedded in accordance with the present invention are: acepromazine, acetaminophen, acetohexamide, acetohydroxamic acid, acetylcholine, acetylcysteine acyclovir, albendazole, alclometasone dipropionate, allopurinol, alprazolam, alprostadil, amcinoide, amantadine, amidinocillin, amikacin amiloride, aminocaproic acid, aminophylline, aminosalicylate, aminosalicylic acid, amitriptyline hydrochloride, ammonium chloride, amobarbital, amodiaquine hydrochloride, amoxapine, amoxicillin, amphetamine sulfate, amphotericin, ampicillin amprolium, acetazolamide acetyldigoxin, acetylsalicylic acid, anileridine, anthralin, antipyrine, antivenin, apomorphine, apraclonidine, ascorbic acid, aspirin, acromycin atropine, amoxycillin anipamil, azaperone azatadine maleate, azathioprine, azithromycin, aztreonam, bacampicillin, bacitracin, baclofen, barium salts, beclomethasone diproionate, belladonna extract, bendroflumethiazide, benoxinate hydrochloride, benzethonium chloride, benzocaine, benzonatate benzthiazide, benztropine mesylate, betaine, betamethasone, betaxolol, betanechol chloride, biotin, biperiden, bisacodyl, bismuth, botulism antitoxin, bromocriptine mesylate, bromodiphenhydramine hydrochloride, bumetanide, bupivacaine, busulfan butabarbital sodium,butalbital, combinations of butalbital, caffeine and aspirin and codeine, beta-carotene, calcifediol, calcium carbonate, calcium citrate, calcium salts, candicidin, captopril, carbachol, carbamazepine, carbenicillin indanyl sodium, carbidopa, carbinoxamine maleate, carboprost tromethamine, carboxymethyl cellulose, carisoprodol, casanthranol, cascara, castor oil, cefaclor, cefadroxil, cefamandole nafate, cefazolin, cefixime, cefoperazone, cefotaxime, cefprozil, ceftazidime, cefuroxime axetil, cephalexin, cephradine, chlorambucil, chloramphenicol, chlordiazepoxide, chloroquine phosphate, chlormadinone acetate, chlorothiazide, chlorpheniramine maleate, chloroxylenol, chlorpromazin, chlorpropamide, chlorprothixene, chlorprothixene, chlortetracycline bisulfate, chlortetracycline hydrochloride, chlorthalidone, chlorzoxazone, cholecalciferol, cholera vaccine, chromic chloride, chymotrypsin, cimetidine, cinoxazin, cinoxate, ciprofloxacin, cisplatin, clarithromycin, clavulanate potassium, clemastine fumarate, clidinium bromide, clindamycin hydrochloride, -palmitate and -phosphate, clioquinol, clofazimine, clofibrate, clomiphene citrate, clonazepam, cinnarizine, clonidine hydrochloride, clorsulon, clotrimazole, cloxacillin sodium, cyanocobalamin, cocaine, coccidioidin, cod liver oil, codeine, colchicine, colestipol, corticotropin, corisone acetate, cyclacillin, cyclizine hydrochloride, cyclobenzaprine hydrochloride, cyclophosphamide, cycloserine, cyclosporine, cyproheptadine hydrochloride, cysteine hydrochloride, danazol, dapsone, dehydrocholic acid, demeclocycline, desipramine, desoximetasone, desoxycorticosterone acetate, dexamethasone, dexchlorpheniramine maleate, dexpanthenol, dextroamphetamine, dextromethorphan, diazepam, diazoxide, dibucaine, dichlorphenamide, dicloxacillin sodium, dicyclomine, dienestrol, diethylpropion hydrochlorid, diethylstilbestrol, diflunisal, digitalis, dicoumarol, digitoxin, digoxin, dihydroergotamine, dihydrostreptomycin, dihydrotachysterol, dihydroxyaluminium amino acetate, dihydroxyaluminium sodium carbonate, diltiazem hydrochloride, dimenhydrinate, dimercaprol, diphenhydramine hydrochloride, diphenoxylate hydrochloride, diphteria antitoxin, dipyridamole, disopyramide phosphate, disulfiram, dobutamine hydrochloride, docusate calcium, docusate sodium, dopamine hydrochloride, doxepin hydrochloride, doxycycline, doxycycline hyclate, doxylamine cuccinate, dronabinol, droperidol, drotaverine, dydrogesterone, dyphylline, guaifenesin, enalapril maleate, analaprilat, ephedrine, epinephrine, equilin, ergocalciferol, ergoloid mesylates, ergonovine maleate, ergotamine tartrate, erythrityl tetranitrate, erythromycin, estradiol, estriol, estrogene, estrone, estropipate, ethcrynic acid, ethambutol hydrochloride, ethchlorvynol, ethinyl estradiol, ethionamide, ethopropazine hydrochloride, ethotoin, ethynodiol diacetate, etidronate disodium, etoposide, eugenol, famotidine, fenoprofen, ferrous fumatate, ferrous gluconate, ferrous sulfate, flucytosine, fludrocortisone acetate, flunisolide, fluocinolone acetonide, fluocinonide, fluorescein sodium, fluorometolone, fluorouracil, fluoxymesterone, fluphenazine, flurandrenolide, flurazpam, flurbiprofen, folic acid, furazolidone, flunitrazepam, furosemide, gemfibrozil, gentamicin, gentian violet, glutarate, glutethimide, glycopyrrolate, chorionic gonadotropin, gramicidin, griseofulvin, guaifenesin, guanabenz, guanadrelsulfate, halazone, haloperidol, haloprogin, halothane, heparin calcium, hepatitis virus vaccine, hetacillin potassium, hexylresorcinol, histamine phosphate, histidine, homatropine, histoplasmin, hydralazine hydrochloride, hydrochlorothiazide, hydrocodone bitartrate, hydrocortisone, hexobarbital, hydroflumethiazide, hydromorphone hydrochloride, hydroquinone, hydroxocobalamin, hydroxyamphetamine, hydroxychloroquine sulfate, hydroxyprogesterone caproate, hydroxyurea, hydroxine hydrochloride, hydroxine pamoate, hyoscyamine, hyoscyamine sulfate, ibuprofen, ifosfamide, imipramide, imipramide hydrochloride, indapamide, indomethacin, insulin, inulin, ocetamid, iodoquinol, iohexol, iopamidol, ipecac, ipodate calcium, ipodate sodium, isocarboxacid, isoetharine hydrochloride, isoflurane,isoniacid, isopropamide iodine, isoproterenol hydrochloride, isosorbide dinitrate, isotretenoin, isoxsuprine hydrochloride, kanamycin sulfate, ketoprofen, ketoconazole, labetalol hydrochloride, lanolin, leucine, leucovorin calcium, levamisole hydrochloride, levocamithine, levodopa, levonorgestrel, levorphanol tartrate, levothyroxine sodium, lidocaine, lincomycin hydrochloride, lindane, liothyronine sodium, liotrix, lisinopril, lithium carbonate, loperamide hydrochloride, loracarbef, lonetil, lorazepam, lovastatin, loxapine, lysine, mafenide acetate, magaldrte, magnesium carbonate, magnesiumchloride, magnesium gluconate, magnesium oxide, other magnesium salts, malathinon, manganese salts, manganese, maprotiline hydrochloride, mazindol, measle virus vaccine, mebendazole, mebrofenin, mecamylamine hydrochloride, meclizine hydrochloride, meclocycline, meclofenamate sodium, medroxyprogesterone acetate, mefenamic acid, megestrol acetate, meglumine, melphalan, menadiol sodium diphosphate, menadione, menotropine, meperidine, mephenytoin, mephobarbital, meprednisone, meprobaamate, mercaptopurine, mesoridazine besylate, mestranol, metaproterenol sulfate, metaraminol bitartrate, methacycline hydrochloride, methadone hydrochloride, methamphetamine hydrochloride, methazolamide, methdilazine, methenamine, methicillin sodium, methimazole, methionine, methocarbamol, methotrexate, methoxsalen, methoxyflurane, methsuximide, methyclothiazide, methylbenzethonium chloride, methyldopa, methylergonovine maleate, methylphenidate hydrochloride, methylprednisolone, methyltestosterone, methysergide maleate, metoclopramide, metolazone, meoprolol tartrate, metronidazole, metyrapone, metyrosine, mexiletine hydrochloride, mexiletine hydrochloride, miconazole, minocycline hydrochloride, minoxidil, mitomycin, mitotane, molindone hydrochloride, monobenzone, morphine sulfate, mupirocin, medazepam, mefruside, methandrostenolone, methylsulfadiazine, nadolol, nafcillin, nafcillin sodium, nalidixic acid, nalorphine, naloxone, nandrolone decanoate, nandrolone phenpropionate, naproxen, natamycin, neomycin, neomycin sulfate, neostimine bromide, niacin, nitrofurantoin, nalidixic acid, nifedipine, nitrazepam, nitrofurantoin, nitroglycerine, nitromerson, nizatidine, nonoxynol 9, norethindrone, norethindrone acetate, norfloxacin, norgestrel, nortriptyline hydrochloride, noscapine, novobiocin sodium, nystatin, opium, oxacillin sodiumn, oxamniquine, oxandrolone, oxazepam, oxprenolol hydrochloride, oxtriphylline, oxybenzone, oxybutynin chloride, oxycodone hydrochloride, oxycodone, oxymetazoline hydrochloride, oxymetholone, oxymorphone hydrochloride, oxyphenbutazone, oxytetracycline, padimate, panreatin, pancrelipase, papain, panthenol, papaverin hydrochloride, parachlorophenol, paramethasone acetate, paregoric, paromomycin sulfate, penicillamine, penicillin, penicillin derivatives, pentaerythritol tetranitrate, pentazocine, pentazocine hydrochloride, pentazocine salts, pentobarbital sodium,

[color emphasis mine, which are names of chemicals, drugs or anti-biotics I recognize]

_____________

continued on subsquent post as the length is too long
« Last Edit: July 17, 2007, 07:06:41 AM by Donna » Logged

Disclaimer:  Opinions, thoughts & premises are my own, except links & quotes.

"Your task is not to seek for love, but merely to seek and find all the barriers within yourself that you have built against it."  Rumi
Donna
Sr. Member
****
Posts: 241

It's PEACE, not war & greed, earthlings!


« Reply #53 on: July 17, 2007, 05:51:13 AM »

continuation ...


perphenazine, pertussis, phenacemide, phenazopyridine hydrochloride, phendimetrazine tartrate, phenelzine sulfate, phenmetrazine hydrochloride, phenobarbital, phenophtalein, phenoxybenzamine hydrochloride, phentermine hydrochloride, phenylalanine, phenylbutazone, phenylephrine hydrochloride, phenylpropanolamine hydrochloride, physostigmine, phytonadione, pilocarpine, pimozide, pindolol, piperazine, piroxicam plicamycin, poliovirus vaccine inactivated, polycarbophil, polymycin b sulfate, polythiazide, potassium chloride, potassium citrate, potassium cluconate, potassium iodine, potassium sodiumn tartrate, povidone iodine, pralidoxime chloride, pramoxine hydrochloride, pramezam, prazepam, praziquantel, prazosin hydrochloride, prazosin hydrochloride, prednisolone, prilocaine, primaquine, primidone, probenecid, probucol, procainamide hydrochlorid, procaine hydrochloride, procarbacine hydrochloride, prochlorperazine, prochlorperazine maleate, procyclidine hydrochloride, progesterone, proline, promazine, promazine hydrochloride, promazine, promethazine, promethazine hydrochloride, propafenone hydrochloride, propantheline, proparacaine hydrochloride, propoxycaine hydrochloride, propoxyphene hydrochloride, propoxyphene napsylate, propanolol hydrochloride, propyliodone, propylthiouracil, propylthiouracil, protriptyline hydrochloride, pseudoephedrine hydrochloride, pumice, pyrantel pamoate, pyrazinamide, pyrethrum extract, pyridostigmine bromide, pyridoxine hydrochloride, pyrilamine maleate, pyrimethamine, pyroxylin, pyrvinium pamoate, phenacetin, phenytoin, prednisone, uinidine gluconate, quinidine sulfate, rabies vaccine, racepinephrine ranitidine, rauwolfia serpentina, resorcinol, ribavirin, riboflavin, rifampin, ritodrine, rubella virus vaccine, saccharin, saccharin sodium, salicylamide, salicylic acid, salsalata, scopolamine, secobarbital sodium, selenius acid, selenium sulfate, sennaserine, simethicone, sodium ascorbate, sodium bicarbonate, sodium fluoride, sodium gluconate, sodium iodide, sodium lactate, sodium nitrite, sodium ditroprusside, sodium salicylate, spironolactone, stannozolol, streptomycin, sucralfate, sulfacetamide, sulfadiazine, reserpine, sulfadioxine, sulfamerazine, sulfamethazine, sulfamethizole, sulfamethoxazole, sulfamethoxydiazine, sulfapyridin, sulfasalazine, sulfaperin, sulfathiazole, sulfisoxazole, sulfinpyrazone, sulindac, suprofen, stilains, tamoxifen citrate, temacepam, terbutaline sulfate, terfenadine, terpin, testolacton, testosterone, tolazamide, tolbutamide, tetracaine, tetracycline, tetrahydrocycline, theophylline, thiabendazole, thiamine hydrochloride, thiamin, thiamylal, thiethylperazine thimerosal, thioguanine, thioridazine hydrochloride, thistrepton, thiotepa, thiothixene, threonine, thyroid, ticarcillin, timolol, tioconazole, titaniumdioxide, tolazamide, tolbutamide, tolmetin, tolnaftate, trazodone hydrochloride, tretinoin, triacetin, triamcinolone, triamterene, triazolarn, trichorfon, trichlonnethiazide, trientine hydrochloride, trifluoperazine hydrochloride, triflupromazine, trihexyphenidyl hydrochloride, trimeprazine tartrate, trimethadione, trimethobenzamide hydrochloride, trimethoprim, trioxsalen, tripelennamine, triprolidine, trisulfapyrimidine, tropicamide, trypsin, tryptohan, tuberculin, tyloxapol, tyropanoate sodium, tyrosine, tyrothricin, thyrothricin bethamethasone, thiotic acid, sotalol, salbutamol, norfenefrine, silymarin, dihydroergotamine, buflomedil, etofibrate, indometacin, urea, valine, valproic acid, vancomycin hydrochloride, vasopressin, verapramil, vidarabine, vinblastine, vincristine, vitamins, warfarin, yellow fever vaccine, zinc acetate, zinc carbonate, zinc chloride, zinc gluconate, beta acetyl digoxin, piroxicam, haloperidol, ISMN, amitriptylin, diclofenac, nifedipine, verapamil, pyritinol, nitrendipin, doxycycline, bromhexine, methylprdnisolone, clonidine, fenofibrate, allopurinol, pirenyepine, levothyroxin, tamoxifen, metildigoxin, o-(beta-hydroxyethyl)-rutoside, propicillin, aciclovir mononitrate, paracetamol, naftidrofuryl, pentoxifylline, propafenone, acebutolol, L-thyroxin, tramadol, bromocriptine, loperamide, ketotifen, fenoterol, cadobelisate, propanolol, enalaprilhydrogen maleate, bezafebrate, ISDN, gallopamil, xantinol nicotinate, digitoxin, flunitrazepam, bencyclane, dexapanthenol, pindolol, lorazepam, diltiazem, piracetarn, phenoxymethylpenicillin, furosemide, bromazepam, flunarizin, erythromycin, metoclopramide, acemetacin, ranitidin, biperiden, metamizole, doxepin, dipotassium chloroazepate, tetrazepam, estramustine phosphate, terbutaline, captopril, maprotiline, prazosin, atenolol, glibenclamide, cefaclor, etilfrine, cimetidine, theophylline, hydromorphone, ibuprofen, primidone, clobazam, oxaceprol, medroxyprogesterone, flecainid, pyridoxal 5 phosphate glutaminate, hymechromone, etofylline clofibrate, vincamine, cinnarizine, diazepam, ketoprofen, flupentixol, molsimine, glibornuride, dimetinden, melperone, soquinolol, dihydrocodeine, clomethiazole, clemastine, glisoxepide, kallidinogenase, oxyfedrine, baclofen, carboxymethylcysteine, thioridazine, betahistine, L-tryptophan, murtol, bromelaine, prenylamine, salazosulfapyridine, astemizol, sulpiride, benzerazide, dibenzepine, acetylsalicylic acid, miconazol, nystatin, ketoconazole, sodium picosulfate, coltyramine, gemfibrocil, rifampicin, fluocortolone, mexiletin, amoxicillin, terfenadrin, mucopolysaccharide polysulfade, triazolam, mianserin, tiaprofenic acid, amezinium metilsulfate, mefloquine, probucol, quinidine, carbamazepine, L-aspartate, penbutolol, piretanide, aescin amitriptyline, cyproterone, sodium valproinate, mebeverine, bisacodyl, 5-aminosalicylic acid, dihydralazine, magaldrate, phenprocoumon, amantadine, naproxen, carteolol, famotidine, methyldopa, auranofme, estriol, nadolol, levomepromazine, doxorubicin, medofenoxate, azathioprine, flutamide, norfloxacin, fendiline, prajmalium bitartrate, lipid derivatives of phosphonatides, amphiphilic polymers, adenosine derivatives, sulfated tannins, monoclonal antibodies, and metal complexes of water soluble texathyrin.  [color emphasis mine]

The amount of the active component or encapsulant which is incorporated into the products of the present invention may be such so as to provide or deliver an effective amount, such as a pharmaceutically effective amount or a nutraceutically effective amount of the active component at its intended location, such as the small intestine. Exemplary amounts of the active component or encapsulant which may be encapsulated or embedded into the matrix may be from about 1% by weight to about 85% by weight, preferably from about 3% by weight to about 50% by weight, based upon the weight of the matrix ingredient, such as starch.

Film-building or film-forming substances which may be used to coat the encapsulants prior to incorporation into the matrix include commonly used coating materials such as zein, pectin, shellac, gelatin, fats, oils, waxes, emulsifiers, native or modified starch, chitosan, chitin, and mixtures thereof. The film-building or film-forming substance may also be used to coat the extruded, particulate product. Pretreatment of the encapsulant by coating it with a film forming substance such as a high melting fat or wax, or with an emulsifier such as glycerin monostearate, or the like, tends to prevent unwanted interaction between an encapsulant and the matrix. The encapsulants and the extrudate particles may be coated with film-forming amounts of the substances in aqueous or alcoholic solutions, or oleaginous compositions

The encapsulated products of the present invention may be incorporated with or without grinding into foods intended for human or animal consumption such as baked goods, for example, bread, wafers, cookies, crackers, pretzels, pizza, and rolls, ready-to-eat breakfast cereals, hot cereals, pasta products, snacks such as fruit snacks, salty snacks, grain snacks, and microwave popcorn, dairy products such as yoghurt, cheese, and ice cream, sweet goods such as hard candy, soft candy, and chocolate, beverages, animal feed, pet foods such as dog food and cat food, aqua-culture foods such as fish food and shrimp feed, and special purpose foods such as baby food, infant formulas, hospital food, medical food, sports food, performance food or nutritional bars, or fortified foods, food preblends or mixes for home or food service use, such as preblends for soups or gravy, dessert mixes, dinner mixes, baking mixes such as bread mixes, and cake mixes, and baking flour. ...
[end quote][/color] [emphasis, including color, mine]

So, tell me, are you astonished by the audacity of the inventions and the end result, including acceptance?  I KNOW I am!  This Patent also refers to "encapsulating" as it relates to necessary anti-biotics and psychopharmaceuticals for humans and animals, and it additionally shows that the accepted Patents simply allow adding viruses, bacterias, vitamins, amino acids, chemicals etc., etc. into pet and human foods at the inventors and assignees whim.  Please keep in mind, all of this is ACCEPTABLE as far as the USPTO is concerned, so each and every subsequent Patent is based on, or refers to Patents 1 of 1.  Finding these components in pet food or animal feeds would not be that surprising to those "knowlegeable in the field", but to those who are not knowledgeable, it is a wake-up call with respect to "additives and nutrients".

Sincerely,
Donna


"The dead cannot cry out for justice; it is a duty of the living to do so for them"
Lois McMaster Bujold, 2002 Diplomatic Immunity, US Science Fiction Author
« Last Edit: July 17, 2007, 07:34:05 AM by Donna » Logged

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"Your task is not to seek for love, but merely to seek and find all the barriers within yourself that you have built against it."  Rumi
JanC
Guest
« Reply #54 on: July 17, 2007, 06:32:27 AM »

WOW.....the things you can dig up......I'm no chemist so it's beyond what I can comprehend.  However, the fact that they are screwing around with food or additives to our food is very obvious.  Perhaps adding it to pf was their first test......obviously, that was a huge failure & many innocent little babies paid dearly for it.  Sort of makes me wonder exactly what WE are eating these days.  With all the diseases that are all too common today & obesity everywhere, sort of makes you wonder.  Frequent urination in animals also brings to mind "overactive bladder" which is very common in people today.  Never heard of that many years ago.  WTF are we eating & feeding to our kids?  Maybe the mass poisoning of pets will soon be mass poisoning of people.....get rid of all these outspoken people who won't believe all the BS we're being fed these days.
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EricV
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Sr. Member
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Posts: 287


« Reply #55 on: July 17, 2007, 06:38:30 AM »

The food additives really make me wonder, as well. I have been sick and in the doctor's office more in the last three months than I have been in my entire life. I'm only 26, so I know that's not very long, but it still seems odd. I currently have a mysterious infection that the doctors can't figure out, and I'm taking 10 pills a day to try to get off of it. The elderly are lucky, since they have lived through much better times, and won't be here as long to face the terrors we all know are coming. I'm afraid we haven't seen anything yet...
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petslave
Hero Member
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Posts: 5178


« Reply #56 on: July 17, 2007, 08:25:33 AM »

Thanks, Donna--that's some astonishing research you've pulled up.  In searching yesterday, I kept getting links among the key words I was using but not able to quite pull them together.  The production of lysine using this bacteria for the process is quite complicated & sounds like its hard getting a uniform product at the end. 

This bacteria is normally found in soils.  It's not the same one that converts atrazine to cyanuric acid that everyone was discussing on another thread, but makes me wonder if this one also is able to do this.  There are a few other bacteria used for the process, so maybe those are also able to convert various substances to toxic chemicals. 

I still haven't been able to find out why the EU was having problems with lysine sulphate produced in the US--they said it HAD to use that particular bacteria for production if it was to be sold there.  Plus specific substrates.  Apparantly mfrs here were not using that process, makes me wonder what they were using.  Here's the link:

http://www.fefana.org/resources/documents/news/Press%20release%20lysine%20sulfate%2006-02-17.doc

I can't seem to find how acetaminophin is made, keep getting links to the recall a few years ago.  Is it strictly chemical, in the lab, in the test tube?  Or can it be converted from one chemical to acetaminophen by biological processes?
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debsue
Full Member
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Posts: 57


« Reply #57 on: July 17, 2007, 09:06:47 AM »

I can't seem to find how acetaminophin is made, keep getting links to the recall a few years ago.  Is it strictly chemical, in the lab, in the test tube?  Or can it be converted from one chemical to acetaminophen by biological processes?

I don't have a lot of time to go thru it right now, but I found this:

http://www.chemheritage.org/EducationalServices/pharm/asp/asp08.htm

Long ago there was a pain reliever called phenacetin. In 1889, eight years before Felix Hoffmann synthesized aspirin, another German scientist, Karl Morner, discovered that the body broke phenacetin down into another compound, acetaminophen. Acetaminophen was actually responsible for reducing pain and fever. No one paid much attention to this discovery until years later, when people learned that phenacetin was really too dangerous to use as a drug. But a small drug company in Pennsylvania called McNeil Laboratories decided to take a look at acetaminophen. It turned out that acetaminophen had all the pain- and fever-reducing power of phenacetin (of course) but was much safer. Since it didn't cause stomach upset like aspirin could, McNeil first sold acetaminophen in 1955 as a pain and fever reliever for children, calling it Tylenol Children's Elixir. Appropriately for an antipyretic, it was sold in a package that looked like a red fire truck.

If you follow the phenacetin link, you find this:

Even before the breakup of Bayer, contraband formulators and smugglers had been making sure that cheaper, albeit illegal, aspirin graced the shelves of the drugstores of North and South America. Many of these products, the fake aspirin alluded to above, were simply cornstarch, or some aspirin mixed with cornstarch or any other white, powdery substance that was cheap and available.

Seems to me we've been talking about a bunch of other white, powdery substances lately.  I'm not sure how this fits in, but I think it's all got to be related.
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debsue
Full Member
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Posts: 57


« Reply #58 on: July 17, 2007, 09:12:27 AM »

Check this link for how to make aspirin:

http://www.departments.bucknell.edu/chemistry/courses/chem212/songs/aspirin.html

 Smiley
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1gone, another on meds
Full Member
***
Posts: 89


« Reply #59 on: July 17, 2007, 09:55:35 AM »

Well - think I'll give this one a try..
 
There are 3 things that jumped out to me regarding our current topic of lysine and cyuarnic acid, all three so closely connected and huge..
 
1) Archer Daniel Midland - major feed supplier -
2) Cargill - major food supplier
3) Dupont - this one is obvious
 
Okay, in my search (namely Archer Daniel Midland) I came across some other forums.  I think it would be interesting to read what others have come up with. 
 
First was this one -
 
From -Thomas Paine's Corner blog Food Contamination:
 
 I suggest we focus on Archer Daniels Midland, the "Supermarket to the World", who have been exposed for doing exactly what the Chinese have been only accused of. Quoting from from Sen.Phil Gramm's wife, who apparently is on ADM's Board of Directors "...ADM has illegally disposed of genetic organisms by adding the organisms to corn glutten (sic) feed. The organisms are in liquid form and are sprayed on the corn glutten feed rather than disposed of as required by the Environmental Protection Agency (EPA). The liquid spray also added weight to the feed. There are other connections to ADM which I won't go into here, but if you're interested, follow this link to Break for News.<BR/>http://breakfornews.com/forum/viewtopic.php?t=2266Anonymoustag:blogger.com,1999:blog-

++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++
Which the above link led me here:
 
Check out this thread by the first poster, the site administrator - as he attempts to connect the dots.. interesting

http://breakfornews.com/forum/viewtopic.php?t=2266
 
snip:
Yes, you read that right. They didn't dispose of the genetically altered
organisims properly --they just sprayed 'em all over their corn gluten.

With the kind of political cover all that money buys, maybe it's no surprise
that the FDA were soooo coy in naming the US company involved in the
tainted pet food scandal:
****************************************************************

Now here is another thread to read.. scroll down to the long one, dated 3/23/2007 @ 5:32 pm..  It's pretty wild, worth a look

http://www.godlikeproductions.com/bbs/message.php?page=3&showdate=3/26/07&messageid=362541&mpage=1
 
 snip:
A search of ADM gluten and ADM wheat gluten connects AMD, our own .gov, genetically modified food, and enough information to boggle your mind to the point it's hard to connect the dots in a manner that someone else could understand it.
****************************************************************
Now here is for friends of the connections.. be sure to click this one - not a feel good feeling at all..

Archer Daniels Midland (ADM)'s Friends
http://www.politicalfriendster.com/showPerson.php?id=285&name=Archer-Daniels-Midland-(ADM)

Personal feeling, we have a lot of info on Archer Daniel Midland and just remember FDA does allow a certain amount of cyaunric acid in livestock feed.  ADM produces lysine and so many other additives...  Maybe we should go from there.. afterall one major USA company was not disclosed, was it?

disclaimer: all in my opinion regarding both public internet searches and personal opinions....
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