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Author Topic: My McTiggerty has lost 3 lbs, since May.  (Read 39220 times)
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BW
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« on: August 06, 2014, 03:23:35 PM »

I took my Tiggerty to the vet today for blood work. He looked so skinny, and I could feel all the bones in his spine all the way down.  He is not eating very much at all.  He is one of my hyperthyroid cats, and takes 1 pill 1st dose and 1/2 pil 2nd dose. 
The vet did blood but must send the thyroid portion out.  The general organs she did in her office.  His kidneys are fine, but his liver numbers are a little below normal, but not too bad.  She gave him fluids.  And then she used a syringe to give him some AD.  He let her, but don't know if he will let me.
She thinks now that he is no longer dehydrated, he may want to eat more. We will see.  So I am awaiting the thyroid numbers, due tomorrow.  She couldn't get any blood from his leg, so took him in the back to get some from his neck.  I HATE that so was glad I didn't have to watch.  He was a very good boy.  He is a sweet cat.
She said I could give him a little of the Tumil-K powder that I just bought for Blackie.
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catbird
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« Reply #1 on: August 06, 2014, 03:33:37 PM »

Sorry to hear about McTiggerty's weight loss. Unfortunately, as the disease progresses, many cats need their methimazole dosage raised. It will be interesting to see if his T4 has increased when the labs are back. I hope his appetite perks up having had the fluids.
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Meowli
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« Reply #2 on: August 06, 2014, 04:28:14 PM »

Sending prayers and good thoughts for McTiggerty, I hope his appetite picks up and he can put some weight back on.
((hugs)) for you. I hate watching their blood drawn too.
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August
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« Reply #3 on: August 06, 2014, 04:29:28 PM »

I'm sorry to hear about this BW.  I'm sending lots of good thoughts your ways and hope McTiggerty will be feeling better and eating more soon.
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GKit
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« Reply #4 on: August 06, 2014, 04:37:03 PM »

I hope the fluids will help McTiggerty eat more and feel better, BW. Sending lots of hugs for you both. Hopefully they can find a methimazole dosage that will work for him.
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lesliek
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« Reply #5 on: August 06, 2014, 04:42:51 PM »

I hope the hydration & possible dosage adjustment make a big difference  ! How old is McTiggerty ? They do tend to lose muscle & get bony with age . Punkin didn't until he hit 22 , but Oreo is starting to now at 17 .
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BW
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« Reply #6 on: August 06, 2014, 05:42:14 PM »

thank you all so much.   Leslie, I have been trying to figure out how old he is.
I can't remember anything any more.  I think he was the litter before the litter during Isabel in 2003.  I must check my records, the vet will have it probably.
But he is not a kid.  Oh my goodness punkin was 22,   what in the world did you feed Punkin!!??  Magic food, I think.
Yes, catbird, I am anxious to hear the results of the T4.  He has been getting the largest dose of all my 4 hyperthyroid cats already.  I hate to increase it.
And thank you Gkit, August, and Meowli for your well wishes.

At least I'm glad his kidneys are ok.  I may have to use a syringe to feed him a bit tomorrow if he doesn't eat by himself.  I have to worry about the fatty liver disease.  He let the vet do it nicely, but for me to do it, I will have to wait and see,  He even hates getting his meds from me.  Tomorrow will tell.  He didn't eat anything tonight.  Bless you all, your support is SOOOO important when you' re alone with a sick cat (S)
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caylee
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« Reply #7 on: August 06, 2014, 06:27:17 PM »

Adding to the many well wishes of the others, and hoping that he will eat for you!

Hugs
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merrihart
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« Reply #8 on: August 07, 2014, 06:39:51 AM »

Many prayers for McTiggerty, BW.  It's tough as they get into their golden years, to keep them feeling good.
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Fizzy1
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« Reply #9 on: August 07, 2014, 12:47:42 PM »

Checking in to see if you have the T4 results yet.  Sending good thoughts to all of you.   Kiss
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BW
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« Reply #10 on: August 07, 2014, 01:06:37 PM »

Well, Tiggerty's numbers were a surprise to the vet. and I don't know how upset I should be.  SHOULD I BE ALARMED!!  HOW DIFFICULT WILL THIS BE TO FIX!!
i FEAR I HAVE DONE IT TO HIM.

I have always heard that HYPO thyroid is extremely difficult to fix, in comparison to HYPER thyroid.  So I am a bit alarmed, tho the vet tried to calm me.

His T4 is now 0.5 low and the range is .8 - 4.0

The vet says this is easily corrected by reducing the medication, but I don't think that is what I have read here.  I hope I am wrong about that.

He was getting 1 whole pill 1st dose and 1/2 pill 2nd dose, and I have always been uncomfortable about those large doses when the other 3 get 1/2 and 1/4 !!
Of course he was a larger cat, now he has lost 3 lbs and is not that large, and doesn't want to eat either.
She says to give him 1/2  1st dose and 1/2  2nd dose now.

So I have been over medicating the poor boy for who knows how long!!!
He hates the 2nd dose and runs and hides every night, it might make him feel lousy and I have thought so for a while, but wanted to be a good cat mom and not let him miss any doses no matter how tired I was.

My little voice has been telling me, it might be too much, but his last blood test in May was ok, so I thought it was my imagination.  HERE ARE HIS LIVER #'S

ALKP 108  RANGE 10 - 90
ALT    121   RANGE  20 - 10      (i DON'T UNDERSTAND THE RANGE FOR THIS)
                                            MAKES IT SEEM LIKE 121 IS DREADFUL )
 So if anyone understands these numbers,
will you please let me know how bad this is.

I know the vet is very careful not to upset me.

She took blood yesterday, and gave him fluids and now she wants him back again tomorrow for more fluids. 
I just took Blackie Monday and then again today, I might as well just move in.

Thank you all.
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catbird
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« Reply #11 on: August 07, 2014, 02:01:52 PM »

BW, with a reduced dose of medication, his T4 should be back in normal range within a week or two. It's only when the cat's T4 is too low after the radiation treatment that fixing it becomes a little more difficult. McTiggerty hasn't had that, so just reducing his med dosage slightly should put it right. I would, however, recommend that he have another test about a month after the medication adjustment is started, just to make sure everything is where it should be.

Loss of appetite is pretty common for cats whose T4 is too low. Once his dose is adjusted, it's likely his appetite will improve.


(Different cats require different dosages of medication to treat hyperT. You might be shocked to know how much methimazole my Isis required near the end of her life.)
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The problem with cats is that they get the exact same look on their face whether they see a moth or an axe-murderer--Paula Poundstone
BW
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« Reply #12 on: August 07, 2014, 03:01:22 PM »

Catbird,  Oh thank the dear Lord!!!  I have been so afraid.  And you can bet your life he will get his T4 tested again as soon as it is called for, (or sooner).
I have been feeding him by putting mushy AD food mixed with a little water, and made warm, on my finger and shoving it in his mouth, yes, he is a very sweet person and he lets me pry open his mouth and shove it in.  then we talk, and he chews, and chews and we talk and then I wipe his mouth and do it again, Kind of like feeding a baby, well exactly like feeding a baby really.

If I am successful next session tonight, I will have gotten 1/2 of a 5.5 can of AD into him today.  He weighs about 8 lbs plus, forgot how many ounces.
He should have more probably, but I am hoping that is enough to prevent fatty liver disease, and I'm praying he may decide to eat himself tomorrow.  Also she wants me to bring him for more fluids tomorrow.
Now he will get 1/2 pill 1st dose and 1/2 pill 2nd dose. I hope that is a big enough reduction to do the job!!

Thank you so much again for your prompt reply, I have been very  upset, and feeling very guilty, altho I did question his big dose in the beginning, but he was a bigger boy then.   I pray this can be fixed soon. 
Bless you for your help.
 
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caylee
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« Reply #13 on: August 07, 2014, 03:50:13 PM »

Keeping you and McTiggerty   Kiss  in my thoughts, BW. I'm glad that catbird was able to put your worst fears to rest with her knowledge. I know nothing about this illness.

Hugs
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Mandycat
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« Reply #14 on: August 07, 2014, 10:44:48 PM »

BW,
Your vet and catbird are absolutely correct.  The dose of methimazole is just too high, and reducing it will increase the T4 to where it should be.  When dose changes are made, the T4 should be checked in 3-4 weeks to be sure that the result is neither too high nor too low.  Weight of the cat has nothing at all to do with the dose of methimazole needed.  Dosage is based on T4 results, not weight at all.  Large cats can require small doses, small cats can require large doses.  The reduction to 1/2 pill twice a day (which is 2.5 mg twice a day) is a reasonable dose, though I don't remember what his T4 was when he was diagnosed and the history of dose increases and T4 results.  Just be sure to retest him to make sure the T4 is okay.  Your goal should be to keep the T4 in the range of 1.5-2.5.

As for the liver enzymes results you posted, something does seem to be wrong with the reference range for the ALT.  That cannot be correct at all, but it might be 10-100.  Both tests are slightly elevated.  We see liver enzymes elevated in hyper-t cats when first diagnosed, but the values return to normal when the T4 is stable.  In this case, I don't think it is the hyper-t that is causing the elevation.  It could be that they were beginning to elevate due to not eating.  Cats are subject to a problem called Hepatic Lipidosis when they do not eat properly for an extended time.  The cure for it is "food", so encourage him to eat and this should resolve itself.  Those results are not very bad, but higher than they should be.  The vet may be using the fluids to also help with this, but also likely that he was somewhat dehydrated and she is hydrating him, which will also improve his appetite.  You should see an improvement in his appetite just from reducing the methimazole also.  Loss of appetite is a symptom of hypo-t.

BTW, just for informational purposes, even when hypo-t happens after the radioiodine treatment, it can be resolved by giving L-thyroxine, which is a thyroid hormone supplement.  Just like methimazole, one needs to find the optimal dose for the cat, but the medication itself is actually less harsh than giving methimazole for hyper-t since it is just replacing something the body normally produces itself - something like women taking hormones for menopause.   
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