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Author Topic: Mitzie's weight loss  (Read 727 times)
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alek0
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« Reply #30 on: September 21, 2017, 07:27:21 PM »

Thanks Ned, helps to know how to give it, if it would help with her nausea it would be great.

She is on Famotidine but I can see that she still has some nausea. Ranitidine works better for her, but it is way to stressful to give since it is liquid and she foams a lot from it and absolutely hates it.

Lactulose is working for her constipation, I am still trying to find the right dose, 2 ml per day is too much (soft poo), 1 ml is kind of close but a bit on the hard side.

I just got back her blood test results, ALT still high but going down, ALKP going down, total protein and globulin high, and as expected creatinine and urea went up since I am feeding her whatever she would eat. Waiting for the vet to call back.

I will likely keep her on some form of appetite stimulant, will try switching over to cyproheptidine since it seems more likely she would continue to eat when appetite stimulant is stopped. I'll add slippery elm and see if that helps as well, and try slowly to stir her back towards more kidney-friendly foods. Will discuss with the vet whether to add Azodyl, waiting for him to call me back.
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lesliek
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Trooper,Remy & Fragile


« Reply #31 on: September 22, 2017, 04:33:05 AM »

Are you giving the lactulose in 1 dose ? It works better given 2-3 times daily for most animals .
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alek0
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« Reply #32 on: September 22, 2017, 07:14:21 AM »

2 times daily, 0.5 ml.
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lesliek
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« Reply #33 on: September 23, 2017, 05:58:56 AM »

Sounds like you just need to play around with dosage to find what works for her .
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alek0
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« Reply #34 on: September 24, 2017, 09:46:11 PM »

Seems the right dosage depends on how much dry she eats. But I guess some soft poo is still better than no poo, so I am aiming at ~1.5 ml per day, 0.75 ml in morning and evening. At that dose, poo is sometimes soft but still mostly well formed, and still only once a day, and sometimes it is textbook perfect poo, depending how much dry she eats. If I give 1 ml per day or less, it can happen that there is no poo until next day when I increase the dose.

I went back over all of her blood test results, and there is this weird thing, whenever ALT goes up, creatinine goes down and vice versa. Once liver starts improving, creatinine goes back up to where it was, it basically oscillates between 215-240 (212 upper limit) and has been like that since january 2016. Globulin has been elevated since May 2016 but my vet didn't think that was very significant, MCV and MCH have been high most of the time but the rest of the blood cell parameters have been in normal range (red blood cells low 2 times but recovered after vit B complex shot), and amylase was often high which my vet did not consider significant.

Anyone has any idea what is going on here?
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