I'm glad to hear they aren't dehydrated.  Hoping for good blood/urine work results.

I am curious--has their weight loss occurred mostly since the Wellness formula change?  (My cats are refusing Wellness more and more since the change.)  How much of their diet does Wellness constitute?

Are abdominal/kidney ultrasounds in the picture, based on the palpation of size difference?  I know that in humans one kidney is often a little smaller than the other, and this is not considered pathological.

I'm wishing Elvis and Davey a good report tomorrow.  Having tests is stressful for our kitties and ourselves.  I know Catbird mentioned ultrasound, however if I were to do it again, not sure I would have put my Maine Coon through it.  He is in the early stages of CRF, just slight elevation on counts.  However, the ultrasound left me depressed as one kidney was so small it was non-functional, the other was functioning but had a lot of past scar tissue.  It stressed him out so bad, that I am afraid each and every time he goes to the Vet now the stress will do him in.  Even having his blood pressure taken he was stressing out big time.  I suppose what I am trying to say if cats do well at the Vet, it may be wise to consider further testing, however if they tend to get stressed, not sure it is worth it.

Good Luck!

Thanks.  My vet did't say anything about x-rays/ultrasounds.  He's been going to the same vet for 18 years.  This is the first time he palpated a change in kidney size.  We're waiting for the lab work and take it from there.  Elvis does not do well at the vet.  He already tends to have elevated blood pressure and pulse rate.  His pulse is usually within normal at home.  He was very upset today, as he usually is.  Davey could care less if he is at the vet and just keeps purring up a storm.  Go figure.

The 2 times they took Elvis' blood pressure in the past, I'm surprised he didn't rip them all to shreds.  He was so upset.  It took 3 people to hold him.

4leggers,

Is your cat on any fluids or medication at this point?

When it comes to going to the Vet, we all wish we had kitties with Davey's personality.

Skeeter is not on any fluids or meds at this point.  In January he showed that he lost about 1 1/2 lbs from his last annual, but hasn't lost any weight since January 08.  Talked to the Vet about him a few weeks ago, he agreed if he is doing good, no need to come in. 

He was on totally dry food till he was 11 (January), I think the switch to canned has helped him maintain weight and keep better hydrated.

Keep us posted. 

Elvis is having additional test run on his blood.  Free T4 to check for hyperthyroidism.

Davey's hematocrit is slightly low, so he is going on Petinic supplementation

Both are going on Epakitin and appetite stimulant.  Both their BUN and creatinines are slightly elevated.

Both have potassiums of 4.3.

Davey's BUN actually went down from a previous 45 to 40 currently.  His creatinine stayed the same 3.4.

Elvis' BUN rose from 41 to 45, his creatinine rose from 3.0 to 3.2. 

Elvis' free-T4 was slightly elevated, 53 (normal range for their lab is 10-50).  I have to discuss with my regular vet when he returns from vacation, starting Tapazole (and the problems with Tapazole and CRF cats).  May have to do another echocardiogram first since he hasn't had one in a year. 

Ho-boy.  This is where it gets complicated.  From when I was getting thyroid tests run every 3 months on Isis, I know that the older the cat, the more toward the bottom of the ranges on thyroid they like them to be.  So slightly over the top of normal might be "wait and see" with a younger cat, but is looked at with more seriousness in an older one.

 But with Elvis' age and beginning CRF, the kidneys may be the primary consideration.  As you know, it's a delicate balance.  Hopes and prayers being sent for finding out just what treatment would be best!

  Elvis.  and {{{hugs}}} JustMe.