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Author Topic: Anyone Using Famotidine?  (Read 49107 times)
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JJ
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« Reply #30 on: January 12, 2010, 09:37:39 PM »

I am posting this just for informational purposes here since the discussion is about Pepcid and Zantac. These drugs are H2 receptor antagonists and decrease the amount of acid in the stomach. In humans, long-term use of these drugs can cause a Vitamin B12 deficiency since B12 requires a certain amount of stomach acid to be properly absorbed. Among other problems, this deficiency can cause peripheral neuropathy in humans.  I do not know what, if any, problems it can cause in dogs and/or cats, but I am posting this so that those of you using these drugs can ask your vets about any possible long-term effects. 
Thanks so much for this info MC. My friend uses the Pepcid everyday for stomach relief and has heart problems. Will bring him a bottle of B12 when I visit so he won't be depleted.
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Mandycat
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« Reply #31 on: January 12, 2010, 09:44:27 PM »

I am posting this just for informational purposes here since the discussion is about Pepcid and Zantac. These drugs are H2 receptor antagonists and decrease the amount of acid in the stomach. In humans, long-term use of these drugs can cause a Vitamin B12 deficiency since B12 requires a certain amount of stomach acid to be properly absorbed. Among other problems, this deficiency can cause peripheral neuropathy in humans.  I do not know what, if any, problems it can cause in dogs and/or cats, but I am posting this so that those of you using these drugs can ask your vets about any possible long-term effects. 
Thanks so much for this info MC. My friend uses the Pepcid everyday for stomach relief and has heart problems. Will bring him a bottle of B12 when I visit so he won't be depleted.

JJ,
Tell your friend he should have blood tests to test for a B12 deficiency.  If he has to take the Pepcid every day, and has been doing so for long-term, he may have it and may need to get the B12 in the form of injections.  Oral B12 is not absorbed very well under these conditions, which is why the deficiency happens to begin with.  The B12 in his food or supplements is not being absorbed because of the low stomach acid caused by taking the Pepcid. 
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lesliek
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Trooper,Remy & Fragile


« Reply #32 on: January 13, 2010, 05:24:57 AM »

Thanks Mandycat, Remy & I & my brother all take it,as well as a few neighbors. 1 more test to be done at checkups.
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JJ
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« Reply #33 on: January 13, 2010, 06:06:39 PM »

MC thx for extra info. Will see him this wkend and make sure he has test done. Lack of this vitamin sure can have serious consequences.

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jenny
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« Reply #34 on: November 19, 2010, 01:31:31 PM »

I am posting this just for informational purposes here since the discussion is about Pepcid and Zantac. These drugs are H2 receptor antagonists and decrease the amount of acid in the stomach. In humans, long-term use of these drugs can cause a Vitamin B12 deficiency since B12 requires a certain amount of stomach acid to be properly absorbed. Among other problems, this deficiency can cause peripheral neuropathy in humans.  I do not know what, if any, problems it can cause in dogs and/or cats, but I am posting this so that those of you using these drugs can ask your vets about any possible long-term effects.  

This isn't an issue for cats.  I am a list owner on a feline IBD list and we asked TAMU about this after a few people read some human research.  Cats process B12 very differently than humans do.  The question we asked them was "Many of the cats on our lists use Pepcid or other H2 acid blockers
either for short-term or long-term management of symptoms. Is there any concern that these could cause B12 malabsorption?"  Steiner's response was 'No'.

Quite a bit of the B12 info is over my head, but it has to do with "intrinsic factor". In humans this is synthesized and secreted in the gastric mucosa, but in cats it is done in the pancreas.  
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lesliek
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« Reply #35 on: November 19, 2010, 05:45:16 PM »

jenny- Did they say anything about dogs too ?
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jenny
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« Reply #36 on: November 20, 2010, 07:56:50 PM »

We didn't specifically ask about dogs, but in his response he did say that there was good evidence for dogs that it was also synthesized through the pancreas.   At least three times we have just posted questions on their web page and Steiner has responded back. 
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KoolKatt
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« Reply #37 on: December 09, 2013, 04:24:02 PM »

Hello furriends,
My Kally Kat has CKD stage 2.

I give her a ¼ tablet in the am before her breakfast & also, another ¼ at her last wet meal of the night!

Famotidine it's the generic version, why & how would it be different than than the real product?

It sure isn't easy pilling her most times I have to use the flat end of a meat pounder to get it to smooth it & then put it in her foods!

For the most part it has been helpful with her stomach acids ( yellow bile)

KoolKat aka Kally Kat
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lesliek
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Trooper,Remy & Fragile


« Reply #38 on: December 09, 2013, 04:40:31 PM »

Compare the ingredient list to the name brand to be sure, but the generic is almost always exactly the same except for price .
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